create a language folder for your country (appropriate folder names are in the format of: en_US, nl_NL, ru_RU, etc...)
copy the .po files to the appropriate folder and then start editing 


Order of picking:
  if there is a cheatengine.po it will pick that, else cheatengine-x86_64.po and if that fails cheatengine-i386.po
  the 32-bit version can work perfectly fine with the 64-bit po


By default it picks the system language, but you can overide this by adding --LANG langstr or -l langstr to the parameters of Cheat Engine


editing po files.
There are some po editing tools but you can also do it by hand
msgid contains the original string and msgstr contains the translated string.
If msgstr is empty the original string will be shown

Certain strings are not present in the cheatengine.po file, but are present in lclstrconsts.po
The lclstrconsts.po file belongs to the LCL that the Cheat Engine GUI is build upon